Some of these pictures and descriptions may give away plot details that you might not want to know before watching the film.
There are three snake appearances in this classic Tim Burton comedy in which two recently-deceased ghosts hire an otherworld exorcist named Betelgeuse (but pronounced "beetle juice") to help them remove the annoying owners of the house they owned when they were alive.
In the main snake scene, we see the father, mother, and daughter walking down stairs along with their snobby friend from New York. The mother discovers that the stairway banister she's holding is a giant snake. Then we see that Betelgeuse has appeared in the form of a gigantic rattlesnake to terrorize them. They all freak out. He pushes the friend downstairs, picks up the father up with his tail and drops him to the floor below and is about to do something nasty to the daughter when the female ghost, who opposes his nasty methods, gets rid of him.
Later, Betelgeuse, still trying to scare them away, puts two snakes in the hand of the father who is near the mother and daughter.
Finally, when the two ghosts go to the waiting room of an afterlife bureaucracy that is full of other recently-deceased souls, we see, in one shot, a man who was killed by swallowing a huge bone that is seen stuck in his throat, a scuba diver who was killed by a shark that is still attached to his leg, and a third man in a sleeping bag with a rattlesnake rattle emerging from it (still shaking and rattling). Apparently he was killed by the bite of a rattlesnake that crawled inside his sleeping bag.
The snakes Betelgeuse hands over are a corn snake and some kind of milk snake, as far as I can tell. The others are special effects.